Dennis Dee Spencer MD

Harvey and Kate Cushing Professor of Neurosurgery; Chair, Department of Neurosurgery; Director, Epilepsy Surgery Program; Director, Pituitary Tumor Program

Departments & Organizations

Yale Medical Group

Office of Student ResearchPituitary Program | Neurosurgery: Epilepsy Surgery; Epilepsy Program

Research Interests

Cerebral metabolic abnormalities that sustain epileptogenesis using MR spectroscopy, Microdialysis, and human tissue studies more...


  • M.D., Washington University, 1971

Selected Publications

  • Eid T, Hammer J, Runden-Pran E, Roberg B, Thomas MJ, Osen K. Davanger S, Laake P, Torgner IA, Lee TS, Kim JH, Spencer DD, Otterson OP, de Lanerolle NC. Increased expression of phosphate-activated glutaminase in hippocampal neurons in human mesial temporal lobe epilepsy. Acta Neuropathol (Berl) 113(2):137-52, 2007.
  • DeLorenzo C, Papademetris X, WuK, Vives KP, Spencer D, Duncan JS. Nonrigid 3D brain registration using intensity/feature information. Med Image Comput Comput Assist Interv Int Conf 9(Pt1):932-9, 2006.
  • Malthankar-Phatak GH, de Lanerolle NC, Eid T, Spencer DD, Behar KL, Spencer SS, KimJH, Lai JCK. Differential Glutamate Dehydrogenase (GDH) Activity Profile in Patients with Temporal Lobe Epilepsy. Epilepsia 47(8):1292-1299, 2006.



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