Richard Arden Bronen MD

Professor of Diagnostic Radiology and of Neurosurgery; Vice Chair, Academic Affairs

Research Interests

Imaging of epilepsy, Cortical dysplasias, Temporal lobe anatomy, and Anatomic variants


Research Summary

Magnetic resonance (MR) imaging is playing an increasingly important role in the evaluation of epilepsy. Human epilepsy is associated with many types of conditions affecting the brain. Thus, the study of epilepsy with MR runs the gamut of cerebral disorders. These include tumors, vascular malformations, hippocampal sclerosis, migration disorders, perinatal insults, infections, trauma, and stroke. MR imaging is particularly important for the patient with medically intractable epilepsy (approximately 30% of epileptics) who may be a candidate for surgical control of their epilepsy, because MR usually detects the responsible lesion and guides decision making and surgical management. Current epilepsy research includes the investigation of MR imaging in the surgical epilepsy group.

Extensive Research Description

Magnetic resonance (MR) imaging is playing an increasingly important role in the evaluation of epilepsy. Human epilepsy is associated with many types of conditions affecting the brain. Thus, the study of epilepsy with MR runs the gamut of cerebral disorders. These include tumors, vascular malformations, hippocampal sclerosis, migration disorders, perinatal insults, infections, trauma, and stroke. MR imaging is particularly important for the patient with medically intractable epilepsy (approximately 30% of epileptics) who may be a candidate for surgical control of their epilepsy, because MR usually detects the responsible lesion and guides decision making and surgical management. Current epilepsy research includes the investigation of MR imaging in the surgical epilepsy group.


Selected Publications

  • Berg AT, Mathern GW, Bronen RA, Fulbright RF, DiMario F, Testa FM, Levy SR. Frequency, prognosis, and surgical treatment of MRI structural abnormalities in childhood epilepsy BRAIN 2009 Jul 28 [Epub]
  • Bilguvar K, Ozturk AK, Louvi A, et. al. Whole exome sequencing identifies WDR62 mutations in severe brain malformations. NATURE 2010:467 (doi:10.1038/nature09327) pp 207-210
  • Vattipally V, Bronen RA. MRI of epilepsy: Overview with emphasis on practical issues. Radiology Clinics of North America 2006
  • Kier EL, Staib L, Davis L, Bronen RA. MRI of the Temporal Stem: Anatomic Dissection Tractography of the Uncinate Fasciculus, Inferior Occipitofrontal Fasciculus, and Meyer's Loop of the Optic Radiation. AJNR 25:677-691, 2004

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